Simon Graham

PhD, P. Eng.
Senior Scientist
sgraham@sri.utoronto.ca
Sunnybrook Health Sciences Centre
Phone: 416-480-4104
Fax: 416-480-4432

Research Assistant:

Lorelie Lacson
Email: Lorelie.Lacson@sunnybrook.ca

Dr. Graham is a medical physicist and biomedical engineer with diverse interests in the development of MRI technology for clinical applications involving the brain. In the past, he has conducted numerous studies aimed at improving the understanding of the biophysical properties of biological tissue that affect MRI signal contrast; improving the method and application of functional Magnetic Resonance Imaging (fMRI) of brain activity in healthy individuals as well as patients suffering from stroke, Alzheimer’s Disease, mild cognitive impairment, brain cancer, and traumatic brain injury; general development and optimization of MRI methods; and detailed numerical simulations, computational methods, and MRI hardware development towards improved use of MRI and associated medical devices (e.g. deep brain stimulators). He has a lengthy track record of successfully leading collaborative research grants and projects.

Education:

  • B.Sc., 1988, engineering physics, Queen’s University
  • PhD, 1995, medical biophysics, University of Toronto

Appointments and Affiliations:

  • Senior scientist, Physical Sciences, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute
  • Professor, department of medical biophysics, U of T

Research Foci

  • Applications of fMRI and MRI in neuroscience
  • Combining functional neuroimaging modalities
  • Functional magnetic resonance imaging (fMRI) of stroke recovery
  • Head motion during functional Magnetic Resonance Imaging (fMRI) of brain activity
  • Virtual reality (VR) and fMRI

Selected Publications

  1. M. Arianpouya, B. Yang, F. Tam, B. Davidson, C. Hamani, N. Lipsman, S.J. Graham. Safe MRI of Deep Brain Stimulation Implants: A Review of the Promises and Challenges. Frontiers in Neurology and Neuroscience Research. 2021 May 31;2:1-23. DOI: 10.51956/FNNR.100012

  2. B. Davidson, F. Tam, B. Yang, Y. Meng, C. Hamani, S.J. Graham, N. Lipsman. 3-Tesla Magnetic Resonance Imaging of Patients With Deep Brain Stimulators: Results From a Phantom Study and a Pilot Study in Patients. Neurosurgery. 2021 Jan 13;88(2):349-355.

  3. Z. Lin, F. Tam, N. Churchill, T. Schweizer, S.J. Graham. Tablet Technology for Writing and Drawing during Functional Magnetic Resonance Imaging: A Review. Sensors (Basel). 2021 Jan 8;21(2):401.

  4. Z. Lin, F. Tam, N.W. Churchill, F-H. Lin, B.J. MacIntosh, T.A. Schweizer, S.J. Graham. Trail Making Test Performance using a Touch-sensitive Tablet: Behavioural Kinematics and Electroencephalography. Front Hum Neurosci. 2021 Jul 1;15:663463.

  5. N.H. Yuen, F. Tam, N. Churchill, T.A. Schweizer, S.J. Graham. Driving with distraction: measuring brain activity and oculomotor behavior using fMRI and eye-tracking. Front Hum Neurosci. 2021;15:413.

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