Paul Karanicolas
Research Assistant:
The focus of Dr. Karanicolas’ research is designing and leading clinical trials in surgical oncology. He has spearheaded the establishment of the HepatoPancreaticoBiliary Community of Surgical Oncologists: Clinical, Evaluative, and Prospective Trials Team (HPB CONCEPT Team), a Canada-wide consensus-based framework for liver and pancreas cancer research. The HPB CONCEPT team’s goals are to improve the care of patients with HPB cancers through investigator-initiated research and to provide a forum for developing high-impact clinical trials.
Dr. Karanicolas is the principal investigator on several grants funded by different organizations, including the Canadian Institutes of Health Research to develop clinical trials on behalf of this group.
Dr. Karanicolas is also involved in several trials as the Co-Chair of the Canadian Cancer Trials Group (CCTG) Hepatobiliary Disease Oriented Group. Dr. Karanicolas also serves as the Medical and Scientific Director of the Centre for Clinical Trial Support at Sunnybrook Research Institute.
Dr. Karanicolas is the surgical lead for the hepatic arterial infusion pump chemotherapy program at the Odette Cancer Centre. This is the first program of its kind in Canada. It offers an additional therapeutic option for patients with colorectal liver metastases.
Education
- MD, 2003, Western University, Canada
- PhD, 2008, health research methodology, clinical epidemiology and biostatistics, McMaster University, Canada
- Resident, 2009, general surgery program, Western University, Canada
- Fellowship, 2011, surgical oncology, Memorial Sloan-Kettering Cancer Center, U.S.
Appointments & Affiliations
- Scientist, Evaluative Clinical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute
- Surgical oncologist, surgical oncology, Sunnybrook Health Sciences Centre
- Sherif and Mary-Lou Hanna Chair in Surgical Oncology Research, Sunnybrook Sciences Health Centre and University of Toronto
- Professor, Department of Surgery, and Institute of Health Policy, Management and Evaluation, University of Toronto
Research Foci
- Clinical trials in surgical oncology
- Hepatopancreaticobiliary surgical outcomes
- Quality of life in patients with cancer
- Quality standards in the processes of care for hepatopancreaticobiliary cancer