Mark I. Boulos
Research Assistant:
Research Assistant:
Dr. Boulos oversees a productive research program that investigates the association of sleep disorders with TIA/stroke & other neurological disorders, as well as examines home sleep monitoring, normative sleep data, and novel treatment interventions for managing sleep disorders. Dr. Boulos has published more than 90 peer-reviewed journal articles in high impact journals such as Lancet Respiratory Medicine, Neurology, Stroke, Chest, Sleep Medicine Reviews, and Sleep.
In addition, he has secured funding on dozens of grants, approximating more than 6.5 million dollars in funding as PI/co-PI. Dr. Boulos’ research is supported by the Canadian Institutes of Health Research, Heart and Stroke Foundation, RLS Foundation, Branch Out Neurological Foundation, the Innovation Fund of the Academic Health Sciences Centres of Ontario, and several industry partners. Moreover, Dr. Boulos has delivered numerous invited lectures at international and national conferences, and his work has also led to appearances with major media outlets such as Yahoo!, CTV news, Toronto Star, Globe and Mail, as well as podcasts with the American Academy of Sleep Medicine, Manulife Insurance, the CBC, and Zoomer Radio.
Furthermore, he has been a mentor to many trainees, and most of his students are authors of the resulting publications. Since starting at Sunnybrook, he has supervised nearly 90 research trainees at all levels of training, from undergraduates to post-doctoral candidates.
In 2020, Dr. Boulos was awarded by the American Academy of Neurology the Wayne Hening Sleep Medicine Investigator Award in recognition of outstanding achievements in Sleep Science research.
Education
- BSc, 2002, University of Toronto, Canada
- MD, 2006, University of Toronto, Canada
- FRCPC, 2011, Adult Neurology Residency, University of Toronto, Canada
- CSCN(EEG), 2012, Canadian Society of Clinical Neurophysiology Certification in Electroencephalography
- MSc, 2013, Stroke and Sleep Neurology, University of Toronto, Canada
- Clinical Research Fellowship, 2013, Stroke and Sleep Neurology, University of Toronto, Canada
- Clinician Investigator Program, 2014, Royal College of Physicians and Surgeons of Canada, Toronto, Ontario, Canada
Appointments & Affiliations
- Senior Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute
- Associate Professor, Department of Medicine, Division of Neurology, University of Toronto
- Staff Neurologist, Department of Medicine, Division of Neurology, Sunnybrook Health Sciences Centre
- Graduate Faculty (Full Member), Institute of Medical Science, School of Graduate Studies, University of Toronto
- Medical Lead, Sunnybrook Sleep Laboratory
- Sleep Neurology Fellowship Program Director, University of Toronto
- Field Editor, Sleep Medicine
- EMR Physician Lead, Barzakay Clinic, Sunnybrook Health Sciences Centre
Research Foci
- Association of sleep disorders with transient ischemic attack (TIA), stroke, dementia/cognitive impairment, spinal cord injury, eye diseases, and other neurological disorders
- Clinical trials
- Clopidogrel (Plavix) pharmacogenetics
- Developing novel approaches to manage sleep disorders
- Establishing normal values for sleep studies
- Home and in-hospital sleep monitoring
- Neurophysiological aspects of sleep (e.g., electroencephalography, eye and limb movement detection)
Affiliated Labs & Programs
Selected Publications
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Boulos MI. The case for improving the detection and treatment of obstructive sleep apnea following stroke. CMAJ. 2023 Mar 14;195(10):E374-E375.
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Boulos MI, Kamra M, Colelli DR, Kirolos N, Gladstone DJ, Boyle K, Sundaram A, Hopyan JJ, Swartz RH, Mamdani M, Loong D, Isaranuwatchai W, Murray BJ, Thorpe KE. SLEAP SMART (Sleep Apnea Screening Using Mobile Ambulatory Recorders After TIA/Stroke): A Randomized Controlled Trial. Stroke. 2022 Mar 1;53(3):710-718.
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Boulos MI, Dharmakulaseelan L, Brown DL, Swartz RH. Trials in Sleep Apnea and Stroke: Learning From the Past to Direct Future Approaches. Stroke. 2021 Jan 1;52(1):366-372.
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Boulos MI, Jairam T, Kendzerska T, Im J, Mekhael A, Murray BJ. Normal polysomnography parameters in healthy adults: a systematic review and meta-analysis. Lancet Respir Med. 2019 Jun 1;7(6):533-543.
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Boulos MI, Murray BJ, Muir RT, Gao F, Szilagyi GM, Huroy M, Kiss A, Walters AS, Black SE, Lim AS, Swartz RH. Periodic Limb Movements and White Matter Hyperintensities in First-Ever Minor Stroke or High Risk TIA. Sleep. 2017 Mar 1;40(3).
In the News
- Polysomnography norms calculator (developed by Dr. Boulos' team)
- Manulife Beyond Age Podcast, Is sleep the key to living a long life?
- Toronto Star, Does cannabis work as a sleep aid? We asked experts about three popular remedies
- Yahoo! Canada, Can naps increase your risk of stroke and high blood pressure? What Canadian experts say