Kullervo Hynynen

Dr. Kullervo Hynynen is an investigator in focused ultrasound technologies and their integration with medical imaging for noninvasive therapies. His groundbreaking work has revolutionized medical treatments, enabling precision interventions like vascular therapies, targeted drug delivery, and noninvasive surgery. A hallmark of his achievements is the development of MRI-guided focused ultrasound systems, now used in clinical practice worldwide.

One of Dr. Hynynen’s most impactful contributions is focused ultrasound treatment for essential tremor, a debilitating condition affecting millions. His innovations have made it possible to use ultrasound energy to ablate brain regions responsible for tremors, providing immediate and sustained relief for patients. This technique, which eliminates the need for invasive surgery, is now an established clinical treatment, improving quality of life for countless individuals.

Dr. Hynynen’s research extends to brain therapies, where he has pioneered the use of focused ultrasound to temporarily open the blood-brain barrier. This breakthrough enables targeted delivery of treatments for challenging conditions like Alzheimer’s disease, Parkinson’s disease, and brain tumors. His work in this area has spurred global clinical trials and opened new possibilities in neurotherapeutics.

Beyond his technical innovations, Dr. Hynynen has advanced the field through leadership in international research networks, collaborations with industry, and mentorship of emerging scientists. His theoretical models and innovative ultrasound transducers continue to push the boundaries of what is possible in noninvasive medical technology, transforming patient care and setting new standards in modern medicine.

Education

• PhD, University of Aberdeen, United Kingdom

Appointments & Affiliations

• Vice-President, Research & Innovation, Sunnybrook Health Sciences Centre
• Senior Scientist, Physical Sciences, Odette Cancer Program, Sunnybrook Research Institute
• Professor, Department of Medical Biophysics, University of Toronto
• Cross Appointed Professor, Institute of Biomedical Engineering, University of Toronto