Research Assistant:
Dr. Detsky’s academic interests are centered on MR-guided adaptive radiotherapy (RT), spine SBRT, and SBRT to the primary and metastases in prostate cancer. As the principal investigator for the UNITED study, he led the development of online adaptive small-margin RT for glioblastoma. Ongoing studies using MR-biomarker driven adaptation will bring forward a paradigm shift in how brain tumors are treated, leveraging advanced technologies like both the MR-Linac and the Synaptive 0.5T MRI. He has published extensively in the field of spine SBRT including its utility and outcomes specific to prostate cancer spinal metastases. Dr. Detsky collaborates widely within Sunnybrook Research Institute and UTDRO regarding biomechanics of spine fractures after RT, brain metastases, and novel PET tracers for gliomas. He co-leads the effort to bring MRCAT (synthetic CT derived from MR images) both to the Odette Cancer Center and beyond to streamline RT simulations.
Education
- B.A.Sc., 2004, Systems Design Engineering, University of Waterloo, Canada
- Ph.D., 2008, Medical Biophysics, University of Toronto, Canada
- M.D., 2013, Faculty of Medicine, University of Toronto, Canada
- Residency, 2018, Department of Radiation Oncology, University of Toronto, Canada
- Fellowship, 2019, Department of Radiation Oncology, Odette Cancer Centre, Canada
Appointments & Affiliations
- Affiliate Scientist, Evaluative Clinical Sciences, Odette Cancer Research Program, Sunnybrook Research Institute
- Staff Radiation Oncologist, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre
- Assistant Professor, Department of Radiation Oncology, University of Toronto
Research Foci
- Adaptive radiotherapy
- Imaging biomarkers
- MR-guided radiotherapy
- Prostate cancer
- Spine SBRT outcomes
Affiliated Labs & Programs
Selected Publications
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Chan et al. Spine Stereotactic Body Radiation Therapy in Geriatric Patients: Implications of Age and Dose on Iatrogenic Vertebral Compression Fracture Risk. Int J Radiat Oncol Biol Phys 2024.
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Moore-Palhares et al. Stereotactic Body Radiation Therapy for Sacral Metastases: Deviation From Recommended Target Volume Delineation Increases the Risk of Local Failure. Int J Radiat Oncol Biol Phys 2024.
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Ong et al. Two-fraction stereotactic ablative radiotherapy with simultaneous boost to MRI-defined dominant intra-prostatic lesion - Results from the 2SMART phase 2 trial. Radiother Oncol 2023.
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Singnurkar et al. 18F-FET-PET imaging in high-grade gliomas and brain metastases: a systematic review and meta-analysis. J Neurooncol 2023.
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Stewart et al. Quantitating Interfraction Target Dynamics During Concurrent Chemoradiation for Glioblastoma: A Prospective Serial Imaging Study. Int J Radiat Oncol Biol Phys 2021.
In the News
- First major advance in radiation treatment for high-grade gliomas in more than 25 years presented at ASTRO 2024.
- MR-Linac on-line weekly adaptive radiotherapy shows positive results for high grade glioma. ecancer.
- Sunnybrook radiation oncologist awarded for presentation of world-first cancer research findings.