Dennis Ko
Despite the dramatic advances in cardiovascular medicine in the last several decades, there remains uncertainty about the application of these advances, particularly in many subgroups of patients that are not generally enrolled in clinical trials. My research has focused on determining optimal clinical strategies and identifying opportunities for improvement in the prevention, treatment and outcome of cardiovascular disease. These research efforts are intended to provide critical information to improve the quality of health care, monitor changes over time, and guide decisions about the allocation of scarce health care resources.
Education
- MD, 1996, University of Ottawa, Canada
- Fellowship, 1999, internal medicine, Cleveland Clinic Foundation, U.S.
- Fellowship, 2002, cardiology, Yale University School of Medicine, U.S.
Appointments and Affiliations
- Director, Schulich Heart Research Program, Sunnybrook Research Institute
- Senior scientist, Evaluative Clinical Sciences, Schulich Heart Research Program, Sunnybrook Research Institute
- Senior scientist, ICES (formerly the Institute for Clinical Evaluative Sciences)
- Interventional cardiologist, Schulich Heart Centre, Sunnybrook Health Sciences Centre
- Associate professor, department of medicine and the Institute of Health Policy, Management and Evaluation (IHPME), University of Toronto
Research Foci
- Appropriateness of invasive procedures
- Cardiac catheterization and percutaneous coronary interventions
- Cardiovascular outcomes
- Meta-analysis
Publications
Affiliated Labs & Programs
Selected Publications
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Sud M, Sivaswamy A, Austin PC, Anderson TJ, Naimark DMJ, Farkouh ME, et al. Development and Validation of the CANHEART Population-Based Laboratory Prediction Models for Atherosclerotic Cardiovascular Disease. Ann Intern Med. 2023;176(12):1638-47.
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Sud M, Han L, Koh M, Austin PC, Farkouh ME, Ly HQ, et al. Association Between Adherence to Fractional Flow Reserve Treatment Thresholds and Major Adverse Cardiac Events in Patients With Coronary Artery Disease. JAMA. 2020;324(23):2406-14.
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Ko DT, Tu JV, Austin PC, Wijeysundera HC, Samadashvili Z, Guo H, et al. Prevalence and extent of obstructive coronary artery disease among patients undergoing elective coronary catheterization in New York State and Ontario. JAMA. 2013;310(2):163-9
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Czarnecki A, Chong A, Lee DS, Schull MJ, Tu JV, Lau C, et al. Association between physician follow-up and outcomes of care after chest pain assessment in high-risk patients. Circulation. 2013;127(13):1386-94
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Ko DT, Guo H, Wijeysundera HC, Natarajan MK, Nagpal AD, Feindel CM, Kingsbury K, Cohen EA, Tu JV, Cardiac Care Network (CCN) of Ontario Variations in Revascularization Practice in Ontario (VRPO) Working Group. Assessing the association of appropriateness of coronary revascularization and clinical outcomes for patients with stable coronary artery disease. J Am Coll Cardiol. 2012 Nov 6;60(19):1876-84.