Clement Hamani

Senior scientist
clement.hamani@sunnybrook.ca
Sunnybrook Health Sciences Centre

Research Assistant:

Sumayya Desai
Email: sumayya.desai@sri.utoronto.ca

The focus of Dr. Hamani’s research is the development of new ways of modulating the function of the nervous tissue, and discovering new applications for techniques that stimulate the brain and spinal cord to treat neurological and psychiatric disorders. His work ranges from basic research in preclinical models to clinical trials.

Education:

  • MD, 1993, Federal University of São Paulo, Brazil
  • PhD, 1996, Federal University of São Paulo, Brazil
  • Residency, 2002, neurosurgery, University of São Paulo, Brazil
  • Fellowship, 2008, functional neurosurgery, University of Toronto, Canada

Appointments and Affiliations:

  • Senior scientist, Biological Sciences, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute
  • Research Director, Hurvitz Brain Sciences Program
  • Professor, department of surgery, U of T

Research Foci

  • Functional neurosurgery
  • Neuromodulation
  • Neuropsychiatric Disorders

Publications

Affiliated Labs & Programs

Selected Publications

  1. Meng Y, Pople CB, Lea-Banks H, Hynynen K, Lipsman N, Hamani C. Focused ultrasound neuromodulation. Int Rev Neurobiol. 2021;159:221-240. doi:10.1016/bs.irn.2021.06.004.

  2. Hamani C, Fonoff ET, Parravano DC, Silva VA, Galhardoni R, Monaco BA, Navarro J, Yeng LT, Teixeira MJ, de Andrade DC. Motor cortex stimulation for chronic neuropathic pain: results of a double-blind randomized study. Brain. 2021 Nov 29;144(10):2994-3004. doi: 10.1093/brain/awab189

  3. Knotkova H, Hamani C, Sivanesan E, Le Beuffe MFE, Moon JY, Cohen SP, Huntoon MA. Neuromodulation for chronic pain. Lancet. 2021 May 29;397(10289):2111-2124. doi: 10.1016/S0140-6736(21)00794-7.

  4. Hamani C, Davidson B, Levitt A, Meng Y, Corchs F, Abrahao A, Rabin JS, Giacobbe P, Lipsman N. Patient with Posttraumatic Stress Disorder successfully treated with Deep Brain Stimulation of the medial prefrontal cortex and uncinate fasciculus. Biol Psychiatry. 2020 Dec 1;88(11):e57-e59. doi:10.1016/j.biopsych.2020.05.018.

  5. Gouveia FV, Davidson B, Meng Y, Gidyk DC, Rabin JS, Ng E, Abrahao A, Lipsman N, Giacobbe P, Hamani C. Treating Post-traumatic Stress Disorder with Neuromodulation Therapies: Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, and Deep Brain Stimulation. Neurotherapeutics. 2020 Oct;17(4):1747-1756. doi: 10.1007/s13311-020-00871-0.

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