
Alan Moody
Magnetic resonance imaging (MRI) has rapidly established itself as a major imaging technique for the visualization of vascular diseases. In particular, magnetic resonance direct thrombus imaging (MRDTI) provides a closer, more in-depth look into occluded arteries, providing information never seen before, and has the potential to change the standard of imaging everywhere. This new MRI technique aims at early diagnosis and intervention to prevent strokes and heart attacks by detecting vulnerable plaques in arteries of patients who are asymptomatic.
Dr. Moody and his team are interested in developing and incorporating such imaging techniques in a comprehensive effort to identify and stabilize vulnerable plaques in one integrated procedure. Applications of MRDTI in the coronary and renal arteries, and aorta are also underway.
The following areas are also under investigation using MRDTI:
- ischemia
- treatment of occlusive vascular disease
- atherosclerotic plaque in the coronary and neurovascular circulations.
Education
- Hon. BA, 1980, physiology, University of Oxford, U.K.
- MBBS, 1983, St. Thomas’s Hospital, U.K.
- FRCP, 1983, Royal College of Physicians, U.K.
- FRCR, 1986, Royal College of Radiologists, U.K.
Appointments and Affiliations
- Senior scientist, Physical Sciences, Schulich Heart Research Program, Sunnybrook Research Institute
- Staff physician, medical imaging, Sunnybrook Health Sciences Centre
- Chair and professor, department of medical imaging, University of Toronto
- Associate professor, Institute of Medical Science, School of Graduate Studies, U of T
- Associate professor, department of medical biophysics, U of T
Research Foci
- Atheroma
- Disease process
- Perfusion
- Thrombosis
- Vascular biology
- Vascular imaging
Publications
Affiliated Labs & Programs
Selected Publications
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Burton KR, Perlis N, Aviv RI, Moody AR, Kapral MK, Krahn MD, Laupacis A. Systematic review, critical appraisal, and analysis of the quality of economic evaluations in stroke imaging. Stroke. 2014 Mar;45(3):807–14.
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Moody A. Perspective: The big picture. Nature. 2013;502,S95.
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Singh N, Moody AR, Rochon-Terry G, Kiss A, Zavodni A. Identifying a high risk cardiovascular phenotype by carotid MRI-depicted intraplaque hemorrhage. Int J Cardiovasc Imaging. 2013 Oct;29(7):1477–83.
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Goeree R, Blackhouse G, Bowen JM, O'Reilly D, Sutherland S, Hopkins R, Chow B, Freeman M, Provost Y, Dennie C, Cohen E, Marcuzzi D, Iwanochko R, Moody A, Paul N, Parker JD. Cost-effectiveness of 64-slice CT angiography compared to conventional coronary angiography based on a coverage with evidence development study in Ontario. Expert Rev Pharmacoecon Outcomes Research. 2013 Oct;13(5):675–90.
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Tardif JC, Spence JD, Heinonen TM, Moody A, Pressacco J, Frayne R, L'allier P, Chow BJ, Friedrich M, Black SE, Fenster A, Rutt B, Beanlands R. Atherosclerosis imaging and the Canadian atherosclerosis imaging network. Can J Cardiol. 2013 Mar;29(3):297–303.